Physiological stress levelAcute and chronic strain
7 / 9Favourable
159
chronic stressacute stressno stress
Your body is coping well with current stress.
Sample report · Example data
Corporate health management · Practice and clinic
Stress Monitor
How your client's body handles stress — and what they can change.
- Parameters
- 6
- Molecular level
- microRNA
- For tracking over time
- all 6
- Genetic analysis
- no
- Result format
- Traffic light 1–9
OverviewOverviewThe six panels compared
The other sample reports: Stress Monitor
The other sample reports
Metabolic HealthHealthy AgingBiological Age ClockTelomere AnalysisHealthy SportAt a glance
Every value in this report
Each value with its classification. One click jumps to the full explanation below.
Sample report · Example data
1 outside the range5 borderline4 within range
- Physiological stress level7 / 9
- Long-term regulation4 / 9
- miR-21-5p8 / 9Long-term regulation
- let-7a-5p7 / 9Stress level
- miR-16-5p6 / 9Long-term regulation
- miR-15a-5p5 / 9Long-term regulation
- let-7g-5p4 / 9Stress level
- miR-106b-5p3 / 9Long-term regulation
- Physiological stress levelFavourable
- Long-term regulationLimited
The principle
Your stress regulation. Not your stress level.
Stress is not a single quantity but a network of neuroendocrine, immunological and metabolic processes — controlled, among other things, via the HPA axis, inflammatory signalling pathways and mitochondrial adaptations. Six microRNAs are analysed: small, non-coding RNA molecules that help determine which genes are actually read under stress conditions.
Acute & chronic
How your stress response is currently running and whether a lasting burden is emerging.
Cellular regulation
How well your body balances stress signals at the cellular level.
Long-term regulation
How regulation turns out at the long-term level — a good current stress level alone says nothing about it.
The process
- 01
Measure
Dried blood spot card, fingertip. Six microRNAs, normalised to the reference gene miR-24-3p. No fasting required.
- 02
Evaluate
Two evaluations on the traffic light 1–9: physiological stress level and long-term regulation.
- 03
Regulate
Targeted recommendations on plant-derived bioactive compounds and follow-up monitoring over time.
How do I read the scale?
Both evaluations and all six individual markers run on the traffic light 1–9. Higher is always better: 1–3 red, 4–6 amber, 7–9 green. Each of the two evaluations additionally carries its own zone labelling.
13579
- 1–3 · Red
- Highest priority.
- 4–6 · Amber
- Take targeted countermeasures.
- 7–9 · Green
- Maintain the result.
The miniature
The report in miniature.
This miniature shows in advance which result formats this report uses. It is calculated from the sample values on this page and is not a picture. Each mark stands for a format that reappears at full size further down — and whatever this panel does not use is missing here as well.
- 1
The traffic light 1–9
Every evaluation sits as a mark on the same traffic light 1–9. Red on the left, green on the right, higher is more favourable. How the marks spread across the band shows directly whether this panel sits more towards the red, amber or green range.
- 2
Two measurements compared
Two measurements of the same value side by side: the open dot is the first, the filled one the second. Only what can actually change is compared — genetic variants stay the same. The interval between two measurements is set by the supervising institution.
Important notices
- Sample report
- All values and personal details in this document are fictitious and serve solely to illustrate the report format. This is not a real report.
- Interpretation
- This report is not a diagnosis and does not replace medical or psychotherapeutic advice. The microRNA values describe a snapshot of cellular regulation; they are not a measurement of perceived stress and make no statement about the presence or development of a disease. If strain, exhaustion, sleep problems or low mood persist, please seek medical advice.
- Status of the analyses
- The analyses are laboratory services provided by our cooperation partner and are not CE-marked in vitro diagnostic devices. They serve consultation and monitoring and do not replace clinical diagnostics. The analyses are supplied to professional users only.
- Legal framework
- This panel evaluates no genotypes; it measures epigenetic markers. Where an analysis in the portfolio does include genetic testing, information and written consent are required before sample collection, and it may only be arranged under medical responsibility (German Genetic Diagnostics Act). The laboratory analysis is carried out by our cooperation partner. Polaris Diagnostics Europe GmbH is responsible for distribution and support. Please review food supplements individually and in consultation with a qualified professional.
Important
This report is not a diagnosis and does not replace medical or psychotherapeutic advice. If strain, exhaustion or sleep problems persist, please seek medical advice.
- The six microRNA values describe a snapshot in time and can be influenced through lifestyle — which makes them suitable for monitoring over time.
How this becomes a consultation
A report is a programme, not a single value.
01
Before the consultation
The full report is available ahead of the appointment. Read it through and mark what stands out: the traffic-light ratings, their distribution across the evaluations, the starting points named. That way it is clear from the outset what to discuss.
02
During the consultation
All six values in this panel sit on the epigenetic level. Unlike genetic variants, which are determined once in a lifetime and remain unchanged, this level responds to nutrition, exercise, sleep and strain — it alone is suitable for tracking progress. The conversation therefore separates what is fixed from what can be worked on.
03
Afterwards
The interval to a follow-up measurement is set by the supervising institution. Laboratory, sample material and sampling should stay the same — and whatever happens in between belongs in the same documentation as the values.
Sample evaluation
The values below come from a complete sample evaluation — exactly as your client receives it. Sample data, not a real person.
- Report for
- Muster, Erika
- Sample collection
- 15.06.2026
- Material
- Dried blood spot card
- Scope
- 6 microRNAs
Results at a glance
Your two evaluations.
Long-term regulationFour microRNAs from four levels of regulation
4 / 9Limited
159
weak regulationmoderate regulationstable regulation
Limited regulation on the slower level.
All microRNAs at a glance
6 values
All microRNAs at a glance
6 valuesThe six individual markers
| microRNA | Designation | Level of regulation | Value | Feeds into |
|---|---|---|---|---|
| miR-21-5p | Cell protection indicator | Cellular protective and adaptive mechanisms | 8 / 9 | Long-term regulation |
| let-7a-5p | Acute stress indicator | Baseline inflammatory regulation | 7 / 9 | Stress level |
| miR-16-5p | Serotonin-regulating indicator | Serotonergic regulation | 6 / 9 | Long-term regulation |
| miR-15a-5p | Neuronal indicator | Neuronal stability and adaptation | 5 / 9 | Long-term regulation |
| let-7g-5p | Chronic stress indicator | Inflammatory and metabolic regulation | 4 / 9 | Stress level |
| miR-106b-5p | Immune signal activating indicator | Immunological activation | 3 / 9 | Long-term regulation |
Table scrolls sideways
The two evaluations are calculated by the laboratory from the microRNAs assigned to them; they are not the average of these individual values.
Evaluation 01
Physiological stress level.
Composed of the acute and the chronic stress indicator (let-7a-5p, let-7g-5p).
7 / 9Favourable
159
chronic stressacute stressno stress
The evaluation shows where your current stress response lies between ‘no stress’ and ‘chronic stress’. Your value is in the favourable range — your body is coping well with current stress. The assessment is always made in the context of the other markers.
The two individual indicators
2 values
The two individual indicators
2 valuesEvaluation 01
let-7a-5pAcute stress indicator
7 / 9
159
Part of the let-7 family; regulates inflammatory signalling pathways and is involved in stress and immune processes. The more favourable of the two values.
let-7g-5pChronic stress indicator
4 / 9
159
Regulates inflammatory and metabolic processes that influence systemic homeostasis. Markedly weaker than the acute indicator.
What matters here
The two individual indicators diverge widely: acute 7/9, chronic 4/9. The acute stress response is working; the chronic level is the weaker of the two.
- Four of the eleven recommendations — quercetin, EGCG, oleuropein and resveratrol — target precisely the chronic indicator let-7g-5p.
Compounds for evaluation 01
4 values
Compounds for evaluation 01
4 valuesRecommendations
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Butyrate | let-7a-5p · 7 | Pectin (apple, rosehip), inulin (chicory, artichoke) | at least 30 g/day | Formed during the fermentation of prebiotic fibre in the gut |
| Quercetin | let-7g-5p · 4 | Onion, capers, lovage, chives | at least 200 mg/day | Heat-sensitive — eat raw or prepare gently |
| EGCG | let-7g-5p · 4 | White or green tea (unfermented) | max. 800 mg/day | Piperine, vitamin C and fish oil improve bioavailability |
| Oleuropein | let-7g-5p · 4 | Olives, olive leaf, argan oil | 100 mg/day | Leaves are 3,000 times more concentrated, but very bitter |
Table scrolls sideways
Evaluation 02
Long-term regulation.
Calculated from four microRNAs: miR-16-5p, miR-15a-5p, miR-106b-5p and miR-21-5p.
4 / 9Limited
159
weak regulationmoderate regulationstable regulation
On the acute level, the evaluation shows no stress-related overload. The slower regulation level, by contrast, sits at 4/9 in the amber range — it is the focus of this report and the starting point for the conversation.
The four microRNAs
4 values
The four microRNAs
4 valuesEvaluation 02
miR-106b-5pImmune signal
3 / 9
159
Regulates immune responses and inflammatory signalling pathways. The only red individual value in this report; four of the eleven recommendations address it.
miR-15a-5pNeuronal
5 / 9
159
Regulates neuronal processes, apoptosis and the cell cycle; influences neuronal homeostasis.
miR-16-5pSerotonergic
6 / 9
159
Regulates serotonergic signalling pathways and the serotonin transporter; involved in neuronal plasticity.
miR-21-5pCell protection
8 / 9
159
Regulates cell survival and apoptosis; involved in stress and repair processes. The best individual value in the entire report.
Compounds for evaluation 02
4 values
Compounds for evaluation 02
4 valuesRecommendations
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Resveratrol | miR-106b-5p · 3 | Grape skins, raspberries, lingonberries, strawberries | 150 mg/day | Hard to achieve through diet alone |
| Omega-3 (PUFAs) | miR-106b-5p · 3 | Oily fish, walnuts, algae, rapeseed and linseed oil | 250–500 mg/day | Keep omega-3 and omega-6 in balance |
| Berberine | miR-106b-5p · 3 | Barberry root bark, orange root | only after professional consultation | Known as a tea from Ayurvedic medicine |
| Folate | miR-16-5p · 6 | Green leafy vegetables, spinach, kale, broccoli | 300 µg/day | Smoking reduces uptake |
Table scrolls sideways
Your interventions
11 values
Your interventions
11 valuesAll recommendations at a glance
Eleven compounds, each assigned to the microRNA marker it acts on, together with that marker’s current value. Sorted by urgency — the weakest markers first.
| Compound | From marker | Source | Amount | Note |
|---|---|---|---|---|
| Resveratrol | miR-106b-5p · 3, let-7g-5p · 4, miR-15a-5p · 5 | Grape skins, raspberries, lingonberries, strawberries | 150 mg/day | Hard to achieve in this amount through diet alone |
| Berberine | miR-106b-5p · 3 | Barberry root bark, orange root | only after professional consultation | Known as a tea from Ayurvedic medicine |
| Butyrate | miR-106b-5p · 3, let-7a-5p · 7, miR-21-5p · 8 | Pectin (apple, rosehip), inulin (chicory, artichoke) | at least 30 g/day | Formed during the fermentation of prebiotic fibre in the gut |
| Omega-3 (PUFAs) | miR-106b-5p · 3, miR-21-5p · 8 | Oily fish, walnuts, algae, rapeseed and linseed oil | 250–500 mg/day | Keep omega-3 and omega-6 in balance |
| Quercetin | let-7g-5p · 4 | Onion, capers, lovage, chives | at least 200 mg/day | Heat-sensitive — eat raw or prepare gently |
| Oleuropein | let-7g-5p · 4 | Olives, olive leaf, argan oil | 100 mg/day | Leaves are 3,000 times more concentrated, but very bitter |
| EGCG (green tea) | let-7g-5p · 4, miR-15a-5p · 5 | White or green tea (unfermented) | max. 800 mg/day | Piperine, vitamin C and fish oil improve bioavailability |
| Folate | miR-16-5p · 6 | Green leafy vegetables, spinach, kale, broccoli | 300 µg/day | Smoking reduces uptake |
| Curcumin | miR-21-5p · 8 | Turmeric | max. 300 mg/day | Check with a doctor in case of pregnancy or gallstones |
| Gingerol | miR-21-5p · 8 | Ginger root | max. 5 g/day | During pregnancy only after consultation |
| Sulforaphane | miR-21-5p · 8 | Cruciferous vegetables, cabbage, broccoli (sprouts) | 25 mg/day | Best raw or briefly steamed |
Table scrolls sideways
Please review food supplements individually and in consultation with a qualified professional — particularly in the case of pregnancy, pre-existing conditions or concurrent medication. This overview does not replace medical advice.
Two measurements compared
Two measurements compared
Trend
A comparison of your two measurements to date. Only measured values are shown — no prognosis.
15.03.202615.06.2026
Physiological stress level
6 / 9→7 / 9+1Favourable
Long-term regulation
5 / 9→4 / 9−1Limited
What the trend shows
The two evaluations are moving in opposite directions: the current stress level has improved from 6 to 7 and is now in the green range. The value for long-term regulation has fallen from 5 to 4 over the same period — and because here too a higher value means more stable regulation, this means that this level has deteriorated.
- This is the real finding of this measurement: acute strain is being coped with better, while the long-term regulatory level has deteriorated. A good stress level alone says nothing about the long-term level.
- The two measurements were around three months apart. The interval until the next follow-up measurement is set by the supervising institution.
Summary
Your focus: the long view.
Your current stress level is good — and that is precisely the point at which this report pushes back: the level that has deteriorated is the one you cannot feel.
01
miR-106b-5p — the only red individual value
At 3/9, the immune signal activating indicator is the weakest value in the report and feeds into long-term regulation. Four of the eleven recommendations target it: resveratrol, berberine, butyrate and omega-3. In concrete terms: at least 30 g of fibre daily for butyrate formation in the gut, 250–500 mg of omega-3 from oily fish, walnuts or algal oil, plus berries for resveratrol.
02
let-7g-5p — the chronic level
At 4/9, the chronic stress indicator lies well below the acute one (7/9) — even though the evaluation as a whole is in the green range. The report does not show which of the two indicators carried the improvement from 6 to 7. Quercetin, EGCG, oleuropein and resveratrol act on the chronic level. The preparation notes differ from compound to compound — details in the table “Your interventions”.
Maintain
miR-21-5p (8/9) and let-7a-5p (7/9) are the two strongest values — cellular protective mechanisms and the acute stress response are working well. Curcumin, gingerol and sulforaphane serve to maintain here, not to correct.
Follow-up and next step
- Your two measurements to date were around three months apart. The interval until the next follow-up is set by the supervising institution.
- For comparability, sample collection and time of day should remain similar.
- In cases of persistent exhaustion, sleep problems or low mood, this report does not replace medical assessment.
Questions about your report?
Discuss the results with the institution that carried out the sample collection. That is where the context needed to interpret them is held.
Contact
- contact@polarisdx.net
- +49 151 75011699
- www.polarisdx.net
Distribution
- Polaris Diagnostics Europe GmbH
- Große Bleichen 1–3
- 20354 Hamburg
Sample report. All values and personal details in this document are fictitious and serve solely to illustrate the report format. This is not a real report.
Interpretation. This report is not a diagnosis and does not replace medical or psychotherapeutic advice. The microRNA values describe a snapshot of cellular regulation; they are not a measurement of perceived stress and make no statement about the presence or development of a disease. If strain, exhaustion, sleep problems or low mood persist, please seek medical advice.
Status of the analyses. The analyses are laboratory services provided by our cooperation partner and are not CE-marked in vitro diagnostic devices. They serve consultation and monitoring and do not replace clinical diagnostics. The analyses are supplied to professional users only.
Legal framework. This panel evaluates no genotypes; it measures epigenetic markers. Where an analysis in the portfolio does include genetic testing, information and written consent are required before sample collection, and it may only be arranged under medical responsibility (German Genetic Diagnostics Act). The laboratory analysis is carried out by our cooperation partner. Polaris Diagnostics Europe GmbH is responsible for distribution and support. Please review food supplements individually and in consultation with a qualified professional.
© 2026 Polaris Diagnostics Europe GmbH · As at: August 2026
All six documents are sample reports: every value, genotype and personal detail is fictitious and serves solely to illustrate the report format. These are not real results.